International heart journalAnimalsPyroptosisMitophagyProtein KinasesRats
USP30 Knockdown Drives Mitophagy and Suppresses Pyroptosis in Heart Failure by Activating the PINK1/Parkin Pathway.
Yanna Yang, Congfei Zhu, Xiaobin Zhou, Xinwei Zhang
Published: 202510.1536/ihj.24-738
Abstract
This study probed into the mechanism of USP30 in mitophagy and pyroptosis during heart failure (HF).A cell model was constructed with oxygen-glucose deprivation (OGD), and an HF rat model was generated by permanently ligating the left anterior descen…
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