Triptolide impedes high glucose-induced cell function in HK2 cells through PRKN-mediated ubiquitination of ACSL1.

Triptolide (TP), a bioactive compound, demonstrates efficacy in ameliorating diabetic nephropathy (DN). This study aimed to investigate the role of TP in renal tubular injury during DN and elucidate the underlying mechanism involving acyl-CoA synthet…

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