Endocrine-related cancerHumansReceptorsGastrointestinal HormoneGrowth Hormone-Secreting Pituitary AdenomaNeuroendocrine Tumors
GIPR in GH-PitNETs: molecular and functional insights.
Mattia Dalle Nogare, Serena Avallone, Eva Galletta, Giorgia Perbellini, Giorgia Pallafacchina, Luna Picello, Daniele Puggina, Mauro Vismara, Gabriele Sales, Giovanni Vazza, Daniela Regazzo, Gianluca Occhi
Published: 202510.1530/ERC-25-0106
Abstract
Acromegaly, primarily caused by GH-secreting pituitary neuroendocrine tumors (GH-PitNETs), in about half of cases exhibits resistance to somatostatin receptor ligands (SRLs), making surgery the primary treatment. Recent evidence suggests that glucose…
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