eNeuro
The neurexin1β histidine-rich domain is involved in excitatory presynaptic organization and short-term plasticity.
Benjamin Feller, Mai Inagaki, Manni Wang, Annika Sivak, Nicolas Chofflet, Hideto Takahashi
Published: 202610.1523/ENEURO.0399-25.2026
Abstract
Neurexins (Nrxns) are presynaptic cell adhesion molecules essential for synapse development and function. Of the many neurexin isoforms, only β-Nrxns contain the histidine-rich domain (HRD). While the HRD has been implicated in several pathological c…
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