Clinical chemistry and laboratory medicine
VeRUS: verification of reference intervals based on the uncertainty of sampling.
Matthias Beck, Florian Dufey, Tatjana Ammer, André Schützenmeister, Jakob Zierk, Christopher M Rank, Manfred Rauh
Published: 202510.1515/cclm-2025-0728
Abstract
OBJECTIVES: Laboratories are required to routinely verify reported reference intervals (RIs), but common verification methods like the CLSI-EP28-A3c binomial test are often impractical due to sample collection requirements. Indirect verification meth…
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