Cellular and molecular biology (Noisy-le-Grand, France)PropiophenonesAnimalsNF-E2-Related Factor 2OsteoarthritisFlavonoids
Xanthohumol suppresses ECM degradation in osteoarthritis through the Nrf2/ PERK/ATF4/C/EBPβ signaling pathway.
Tiansheng Zheng, Shuo Niu, Qingluo Zhou, Jishang Huang, Jun Yi, Runhong Mei, Xuefeng Yu
Published: 202510.14715/cmb/2025.71.11.3
Abstract
In this study, the therapeutic efficacy of Xanthohumol (XH) was evaluated as a preventive agent for extracellular matrix (ECM) degradation in osteoarthritis, using the in vivo monosodium iodoacetate-induced arthritis model in rats, along with the in…
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