Histology and histopathology
1,25-Dihydroxyvitamin D3 mitigates high glucose-induced oxidative stress, inflammation, and extracellular matrix accumulation in glomerular mesangial cells via the ROS/TXNIP/NLRP3 pathway.
Qingyue Meng, Bo Chen, Chunjiang Zhang, Lin Jia, Xingyu Yao, Gang Liu
Published: 202510.14670/HH-25-021
Abstract
BACKGROUND: 1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) is a physiologically active form of vitamin D. Our study investigated the renoprotective functions of 1,25(OH)2D3 in diabetic nephropathy (DN) progression and its underlying mechanism targeting the R…
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