PLoS pathogens
White spot syndrome virus IE1 protein hijacks the host pentose phosphate pathway to fuel viral replication.
Jia Zhang, Kaiyu Lu, Jinghua Zhu, Jude Juventus Aweya, Yueling Zhang, Defu Yao
Published: 202610.1371/journal.ppat.1013913
Abstract
Viruses frequently reprogram host metabolism to support their replication. The pentose phosphate pathway (PPP), a key regulator of nucleotide synthesis and redox balance, is often targeted during infection. While PPP activation is well-known proviral…
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