PLoS pathogens
Tissue-resident macrophage and dendritic cells drive type I IFN immunity to enteroviruses in the liver.
Emma Heckenberg, Jacob G Davis, Caitlin Hale, Carolyn B Coyne
Published: 202610.1371/journal.ppat.1013891
Abstract
Enteroviruses are major causes of neonatal morbidity and mortality, with echovirus infections commonly associated with severe disease, including acute liver failure. The human neonatal Fc receptor (hFcRn) is the primary receptor for echoviruses, and…
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