PLoS pathogens
Multifaceted B cell response to transient HIV viremia in elite controllers.
Luke Muir, Ondrej Suchanek, Peter Thomas, Sarah A Griffith, Emma Touizer, Chloe Rees-Spear, Robert Krause, Masahiro Yoshida, Christopher L Pinder, Rutuja Patil, Marko Z Nikolic, Katie J Doores, Marit J Van Gils, Alasdair Leslie, Alex Sigal
Published: 202610.1371/journal.ppat.1013817
Abstract
Chronic HIV infection drives B cell dysfunction associated with the accumulation of tissue-like memory (TLMs) and activated memory B cells (MBCs) but decline in resting memory B cells. TLMs express multiple inhibitory receptors and lack response to s…
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