PLoS pathogens
The receptor binding properties of H5Ny influenza A viruses have evolved to bind to avian-type mucin-like O-glycans.
Julia Weber, Niels L D Ponse, Xueyong Zhu, María Ríos Carrasco, Alvin X Han, Mathis Funk, Ting-Hui Lin, Alba Gabarroca García, Cindy M Spruit, Ding Zhang, Wenli Yu, Ian A Wilson, Mathilde Richard, Geert-Jan Boons, Robert P de Vries
Published: 202610.1371/journal.ppat.1013812
Abstract
Highly pathogenic H5Ny influenza A viruses are causing unprecedented, season-independent outbreaks across avian and mammalian species, including dairy cattle, a novel reservoir. The sialoside-binding properties of influenza A hemagglutinin (HA) are s…
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