PLoS computational biologyAnimalsCattleCollagenCartilageArticular
MMP release following cartilage injury leads to collagen loss in intact tissue: A computational study.
Moustafa Hamada, Atte S A Eskelinen, Joonas P Kosonen, Cristina Florea, Alan J Grodzinsky, Petri Tanska, Rami K Korhonen
Published: 202610.1371/journal.pcbi.1013209
Abstract
Collagen damage in articular cartilage plays a key role in post-traumatic osteoarthritis, but the underlying mechanobiological pathways leading to collagen fibril degeneration after injury remain incompletely understood. We hypothesized that mechanic…
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