Optimized Molecular Weight of Hydroxypropyl Cellulose in Inhaled Spray-Freeze-Dried Powders for High Deagglomeration and Pulmonary Retention Abilities.

Mucociliary clearance is a unique defense mechanism that forcibly transfers micron-sized substances deposited on the airway epithelium from the lungs, but may interfere with inhalation therapy. The application of mucoadhesive agents to inhaled formul…

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