Biological & pharmaceutical bulletinVancomycinHumansAnti-Bacterial AgentsArea Under CurveMale
Comparison of Trough-Only and Peak-Trough Concentration Data for the Calculation of Vancomycin Area under the Concentration-Time Curve on Day 1 or Day 2.
Momoka Endo, Takashi Niwa, Yuto Yamada, Ayasa Goto-Fujibayashi, Kazuyuki Sumi, Manami Otsubo, Natsuki Ichihashi, Koki Hara, Ryohei Miyashita, Akio Suzuki
Published: 202510.1248/bpb.b25-00562
Abstract
Area under the concentration-time curve (AUC)-guided vancomycin dosing is recommended to measure peak and trough concentrations. While recent studies have shown that AUC on Day 1 and Day 2 are associated with early clinical response and nephrotoxicit…
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