Cell structure and function
Single-nucleosome imaging uncovers biphasic chromatin dynamics in inducible human transformed cells.
Aoi Otsuka, Masa A Shimazoe, Shigeaki Watanabe, Katsuhiko Minami, Sachiko Tamura, Tohru Kiyono, Fumitaka Takeshita, Kazuhiro Maeshima
Published: 202510.1247/csf.25147
Abstract
In higher eukaryotic cells, genomic DNA is packaged into dynamic chromatin domains whose physical behavior is coupled to DNA transactions such as transcription and DNA repair. Although chromatin organization is altered in cancer, how oncogenic signal…
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