Annals of surgical oncology
Shifting Paradigm: Utilization and Outcomes with Neoadjuvant Chemotherapy for cT4 and cN2 Colon Cancers.
Bennett W Hartley, Vivi W Chen, Punam Amin, Atif Iqbal, Yesenia Rojas-Khalil, Eugene Choi, Christy Chai, Ernest R Camp, Derek J Erstad
Published: 202610.1245/s10434-025-19072-0
Abstract
BACKGROUND: Upfront surgical resection (USR) remains the standard of care for resectable, nonmetastatic colon cancer. However, for locally advanced (cT4) and high nodal burden (cN2) disease, we hypothesized that neoadjuvant chemotherapy (NAC) would b…
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