Annals of surgical oncology
Combined Impact of Neoadjuvant Therapy and Preoperative Cachexia in Patients Undergoing Pancreatoduodenectomy: Is There a "Double Jeopardy"? A National Cohort Study Investigating the Association with Short- and Long-Term Outcomes.
Marcus Thomas Thor Roalsø, Celine Oanaes, Herish Garresori, Karin Hestnes Edland, Ingvild Dalen, Hanne Røland Hagland, Kjetil Søreide
Published: 202610.1245/s10434-025-18941-y
Abstract
BACKGROUND: Cachexia is associated with worse postoperative outcomes, but the added role of neoadjuvant therapy (NAT) is unclear. This study evaluated whether preoperative cachexia and NAT act as a "double jeopardy" after pancreatoduodenectomy. PATIE…
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