Annals of surgical oncology
Absolute Bioavailability of Oxaliplatin After Intraperitoneal Administration by Electrostatic Pressurized Intraperitoneal Aerosol Chemotherapy (ePIPAC): Systemic Pharmacokinetics of the CRC-PIPAC-II Trial.
Teun B M van den Heuvel, Paulien Rauwerdink, Emma Hulshof, Vincent C J van de Vlasakker, Dirk Jan A R Moes, Giulia Pluimakers, Koen P B Rovers, Geert-Jan Creemers, Pim J W A Burger, Simon W Nienhuijs, René J Wiezer, Robin J Lurvink, Djamila Boerma, Ignace H J T De Hingh, Maarten J Deenen
Published: 202610.1245/s10434-025-18874-6
Abstract
BACKGROUND: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) offers a localized palliative treatment option for patients with colorectal peritoneal metastases (CPM), often combined with systemic therapy to maximize anti-tumor efficacy. This s…
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