Annals of surgical oncology
Hepatectomy Plus Chemotherapy or Chemotherapy Alone for Resectable Liver and Unresectable Lung Metastases from Colorectal Adenocarcinoma (LUNA): A Randomized Phase II Trial.
Ian W Folkert, Reza Mehran, Ryan Sun, Van K Morris, Michael J Overman, Bryan Kee, Mara B Antonoff, Ching-Wei Tzeng, Arvind Dasari, Hop Tran Cao, Christine M Parseghian, Eduardo Vilar, Jason Willis, Timothy E Newhook, Wayne Hofstetter
Published: 202510.1245/s10434-025-18854-w
Abstract
BACKGROUND: Hepatectomy for isolated colorectal liver metastases is associated with 5 year overall survival (OS) of 58% and is accepted as standard of care. However, the role of liver resection with unresectable low-volume lung metastases is unknown.…
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