Annals of surgical oncology
Germline BRCA1/2 Mutation Prevalence in Unselected ER-Low/HER2-Negative Breast Cancer.
Ji Won Yoo, Jinyoung Byeon, Woong Ki Park, Jisun Kim, Han-Byoel Lee, Sung Gwe Ahn, Seung Ho Baek, Su Min Lee, Se Kyung Lee, Byung Joo Chae, Jonghan Yu, Jeong Eon Lee, Seok Won Kim, Seok Jin Nam, Hyunwoo Lee
Published: 202510.1245/s10434-025-18713-8
Abstract
BACKGROUND: Estrogen receptor (ER)-low breast cancers, defined as tumors with 1-10% ER expression, exhibit clinicopathologic and molecular features, as well as chemotherapy responses, resembling triple-negative breast cancer (TNBC), leading to update…
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