Annals of surgical oncology
Comparative Analysis of PIPAC Nozzle Designs: Ex Vivo Evaluation of Aerosol Distribution, Penetration, and Tissue Concentration.
Elias Karam, Fabian Kockelmann, Valentina Romdhane, Sarah Barbey, Roselyne Viel, Anthony Sébillot, Sébastien Roger, Nicolas Michot, Urs Giger-Pabst, Mehdi Ouaissi
Published: 202510.1245/s10434-025-18675-x
Abstract
BACKGROUND: A comparative ex vivo study was conducted to evaluate the impact of different nebulizer designs on spatial distribution, tissue concentration, and penetration depth of drugs delivered via pressurized intraperitoneal aerosol chemotherapy (…
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