Disease models & mechanisms
Ttc21b is required for proper forebrain neural progenitor proliferation.
Rebekah Niewoehner, David Paulding, Jesus M Leal, Rebekah Rushforth, Rolf W Stottmann
Published: 202510.1242/dmm.052392
Abstract
Primary cilia play a pivotal role in cellular signaling and development. Human primary microcephaly is strongly associated with pathogenic variants in primary cilia genes. Here, we examine the role of Ttc21b, a component of the intraflagellar transpo…
Preview only. Read the full abstract at the source