Development (Cambridge, England)AnimalsHumansMiceHedgehog ProteinsNeural Tube
The people behind the papers - Sun-Hee Hwang, Eric Brooks and Saikat Mukhopadhyay.
Published: 202510.1242/dev.205408
Abstract
Hedgehog (HH) signalling is crucial for nervous system patterning. Genetic variants in key HH regulators, such as Gpr161, have been clinically linked to cranial neural tube closure defects (exencephaly) - a congenitally lethal condition. However, the…
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