Anesthesia and analgesia
Are "GABAergic" Agents Really So Selective for GABA? Implications for Single- versus Multi-Site Hypotheses From Promiscuous Behavior of Anesthetics and Their Molecular Targets In Vitro.
Kush M Kale, Peter A Goldstein, Jaideep J Pandit
Published: 202610.1213/ANE.0000000000007888
Abstract
In the literature, anesthetic agents are commonly described as if their hypnotic action is mediated by a predominant molecular target, using terminology such as "GABAergic" or "NMDAergic." The justification for this is unclear. The authors might ther…
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