Endocrinology
Metformin in Obese Pregnancy: Developmental Reprogramming of Offspring Liver and MASLD Risk by Age and Sex.
Elena Müller-Limberger, Bettina Frederick, Sebastian Hansen, Maria Wohlfarth, Philipp Kasper, Ruth Janoschek, Esther Mahabir, Pascal Fischer, Andrea Mesaros, Martin Purrio, Alexander Quaas, Miguel A Alejandre Alcázar, Jörg Dötsch, Eva Hucklenbruch-Rother, Sarah Appel
Published: 202510.1210/endocr/bqaf188
Abstract
Maternal obesity before and during pregnancy causes maladaptive foetal development with long-term effects on offspring's metabolic health, including a higher risk of metabolic dysfunction-associated steatotic liver disease (MASLD). Treatment with met…
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