The Journal of clinical endocrinology and metabolism
Tumor-infiltrating T Lymphocytes Recognize Thyroid-specific and Neo-antigens in Follicular Cell-derived Thyroid Cancers.
Breaunna Garza, Jacob Calhoun, Paul Norman, Noah Cline, Katherine M Kichula, Ticiana D J Farias, Sharon Sams, Meher Preethi Boorgula, Thomas Danhorn, Bryan R Haugen, Jena D French
Published: 202510.1210/clinem/dgaf639
Abstract
BACKGROUND: Thyroid cancers are among the growing list of cancer types that are resistant to immune-checkpoint inhibitor (ICI) monotherapy. While T cell infiltration is common in follicular cell-derived thyroid cancers, tumor mutation burden is low.…
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