The Journal of clinical endocrinology and metabolism
Bioactive Insulin-like Growth Factor (IGF)-I Concentrations in Children on Growth Hormone Therapy.
Lea Vilmann, Jakob Albrethsen, Jørgen Holm Petersen, Stine Agergaard Holmboe, Peter Christiansen, Katharina Maria Main, Line Cleemann, Kristian Horsman Hansen, Jan Frystyk, Casper P Hagen, Anders Juul
Published: 202510.1210/clinem/dgaf566
Abstract
BACKGROUND: Monitoring Insulin-like Growth factor (IGF)-I concentration is recommended during Growth Hormone (GH) therapy (GHT) in children. Supranormal levels of total IGF-I have raised concerns of long-term risks. AIM: To evaluate bioactive and tot…
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