The AAPS journalHumansMidazolamModelsBiologicalAdult
Virtual Twin-PBPK Modelling: A Step Toward Precision Dosing in Patients with Obesity.
Haribhau Kangne, Nihan Izat, Gong Chen, Kayode Ogungbenro, Rasmus Jansson-Löfmark, Jens K Hertel, Ida Robertsen, Aleksandra Galetin
Published: 202610.1208/s12248-025-01195-7
Abstract
Obesity significantly alters drug disposition and contributes to large inter-individual variability in pharmacokinetics (PK). The virtual-twin concept is increasingly used to support model-informed precision dosing in specific populations. In this st…
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