The AAPS journalAnimalsMetronidazoleModelsBiologicalSpecies Specificity
Metronidazole Pharmacokinetics Across Species: Meta-Analysis Integrating Allometric Scaling and Minimal Physiologically-Based Pharmacokinetic Modeling.
Fatma Kir, William J Jusko
Published: 202510.1208/s12248-025-01191-x
Abstract
Metronidazole (MTZ) is frequently used in both human and veterinary medicine to treat infections caused by certain protozoa and anaerobic bacteria. This study investigates the pharmacokinetic (PK) profiles of MTZ for available species in the literatu…
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