The AAPS journalHumansMigraine DisordersPlacebo EffectChronic DiseaseMale
Meta-Analysis of the Placebo Response in Chronic and Episodic Migraine: Insights from Migraine Preventive Drug Trials.
Anantha Ram Nookala, Nimishraj Panse, Gopichand Gottipati, Heather D Fitter, Ramana Uppoor, Mehul Mehta, Sreedharan Sabarinath
Published: 202510.1208/s12248-025-01181-z
Abstract
Randomized, well-controlled trials are the gold-standard for evaluating novel therapies, but they often fail to fully account for the placebo response, particularly in pain-related conditions such as migraine, where subjective improvement is common i…
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