Journal of clinical oncology : official journal of the American Society of Clinical OncologyHumansMaleAntineoplastic Combined Chemotherapy ProtocolsPancreatic NeoplasmsFemale
TRYBECA-1: A Randomized Phase III Study of Eryaspase Combined With Chemotherapy Versus Chemotherapy as Second-Line Treatment in Patients With Advanced Pancreatic Adenocarcinoma.
Pascal Hammel, Jean-Philippe Metges, Teresa Macarulla Mercade, Rocio Garcia-Carbonero, Olivier Bouché, Fabienne Portales, Roberto A Pazo Cid, Laurent Mineur, Antonio Cubillo Gracian, Isabelle Trouilloud, Rosine Guimbaud, David Tougeron, Juan Jose Reina, Jaime Feliu, Tamara Sauri
Published: 202510.1200/JCO-25-00872
Abstract
PURPOSE: This phase III (ClinicalTrials.gov identifier: NCT03665441) study evaluated eryaspase in combination with chemotherapy as second-line treatment in advanced pancreatic ductal adenocarcinoma (PDAC). PATIENTS AND METHODS: TRYBECA-1 enrolled pat…
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