Journal of clinical oncology : official journal of the American Society of Clinical OncologyFemaleHumansMaleAntineoplastic Combined Chemotherapy ProtocolsBiomarkers
Individual Patient Data Meta-Analysis of Consensus Molecular Subtypes as Biomarkers of First-Line Treatment in RAS Wild-Type Metastatic Colorectal Cancer.
Arndt Stahler, Dominik Paul Modest, Sebastian Stintzing, Beatrice Borelli, Theresa Keller, Swantje Held, Ludwig Fischer von Weikersthal, Lothar Müller, Ullrich Graeven, Thomas Decker, Tobias Heintges, Christoph Kahl, Beeke Hoppe, Alexander Kiani, Florian Kaiser
Published: 202610.1200/JCO-25-00596
Abstract
PURPOSE: Consensus molecular subtypes (CMSs) of metastatic colorectal cancer (mCRC) are debatable biomarkers. An individual patient data (IPD) meta-analysis was performed to test for impact on objective response rates (ORRs), progression-free surviva…
Preview only. Read the full abstract at the source