JCO clinical cancer informaticsHumansNeoplasmsDose FractionationRadiationLymphopenia
Tumor Site-Specific Radiation-Induced Lymphocyte Depletion Models After Fractionated Radiotherapy: Considerations of Model Structure From an Aggregate Data Meta-Analysis.
Thao-Nguyen Pham, Julie Coupey, Samuel Valable, Juliette Thariat
Published: 202510.1200/CCI-25-00144
Abstract
PURPOSE: Radiotherapy can have an impact on the immune system through lymphocyte depletion. In particular, it can influence tumor control. Accurately predicting radiation-induced lymphopenia (RIL) is key to optimizing treatment strategies. We aimed t…
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