The British journal of psychiatry : the journal of mental science
Examining the safety profile of clozapine versus other antipsychotics: systematic review and meta-analysis.
Elisavet Pinioti, Eleni Glarou, Andreas S Lappas, Iwo Fober, Bartosz Helfer, Spyridon Siafis, Nikos Christodoulou, Adriani Nikolakopoulou, Stefan Leucht, Myrto Samara
Published: 202510.1192/bjp.2025.10421
Abstract
BACKGROUND: Antipsychotics are first-line treatments for schizophrenia, yet many patients show inadequate response. Clozapine, the gold standard for treatment-resistant schizophrenia, remains underutilised due to safety and monitoring concerns. AIMS:…
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