Advances in rheumatology (London, England)
The efficacy and safety of tocilizumab in juvenile localised scleroderma patients: a retrospective cohort study in Eastern China.
Yang Shen, Xiaoliang He, Jing Shan, Denghuan Chen, Yutong Gao, Xinrong Wang, Dingyun Chen, Shouwei Hang, Na Li, Daliang Xu
Published: 202510.1186/s42358-025-00511-1
Abstract
BACKGROUND: Localised scleroderma is a rare autoimmune connective tissue disorder characterized by excessive collagen deposition leading to skin fibrosis. While methotrexate and glucocorticosteroid remain the first-line treatments, their limitations…
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