Biological research
Lifelong cGAS deficiency leads to altered lipid storage and cholesterol homeostasis.
Daniela Carrillanca, Ian Riquelme, Matías Mansilla-Jaramillo, Camila Sánchez-Pérez, Andrea Monterroza, Natalia Lepio, Fabián Rojas, Gonzalo I Cancino, Paola Murgas
Published: 202610.1186/s40659-026-00669-y
Abstract
BACKGROUND: The complex interaction between the immune system and metabolic homeostasis is becoming recognized, as immune sensors affect key metabolic tissues, including the liver and adipose tissue. The cGAS-cGAMP-STING pathway, previously recognize…
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