BMC pharmacology & toxicology
Decrypting potential mechanisms linking ochratoxin A to hepatocellular carcinoma: an integrated approach combining toxicology, machine learning, molecular docking, and molecular dynamics simulation.
Junyi Zhuo, Hua Wu, Xiaoling Zhou, Xi Wang, Tianqi Qiu, Min Lin, Yu Tang
Published: 202610.1186/s40360-026-01092-5
Abstract
BACKGROUND: Ochratoxin A (OTA), a common food-borne mycotoxin, is a potential human carcinogen, yet the specific molecular mechanisms linking it to hepatocellular carcinoma (HCC) remain unclear. METHODS: We integrated network toxicology to predict OT…
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