European journal of medical research
Targeted next-generation sequencing has comparable clinical value to metagenomic NGS for pulmonary infections in hematological malignancy patients: a real-world propensity score-matched study.
Yulian Xiao, Yishu Tang, Yuhan Yan, Qian Cheng, Xin Chen, Liwen Wang, Xin Li
Published: 202610.1186/s40001-026-03893-0
Abstract
BACKGROUND: Metagenomic next-generation sequencing (mNGS) is widely recognized in immunocompromised populations due to its unbiased ability to identify pathogens, while targeted next-generation sequencing (tNGS) combines PCR amplification with high-t…
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