European journal of medical research
Mechanism of ultrasound-guided renal parenchymal injection of MSCs for the treatment of chronic kidney disease: down-regulated SGK1 promotes M2 macrophage polarization.
Shanshan Wan, Daiyuan Tang, Zuozhang Yang, Yingqing Zeng, Long Hu, Liangyu Zhu, Chunjuan Xia, Fukai Bao, Changxing Ke, Jiaping Wang
Published: 202610.1186/s40001-025-03724-8
Abstract
BACKGROUND: Chronic kidney disease (CKD) often progresses to renal fibrosis, leading to irreversible kidney damage and a decline in renal function. This study explores the therapeutic effects of ultrasound-guided mesenchymal stem cells (MSCs) infusio…
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