Cell & bioscience
In vitro mimicking of humanized cardiogenesis under porcine condition.
Jiajun Li, Changjiang Xu, Bingbo Shi, Yawen Lyu, Zejie Lin, Wei Shi, Jiachen Xu, Xinle Zou, Xiaomin Wang, Hanqing Zhao, Chengchen Zhao, Duanqing Pei
Published: 202610.1186/s13578-025-01521-8
Abstract
BACKGROUND: One promising strategy to generate humanized organs is through embryo complementation by injecting human pluripotent stem cells (PSCs) into gene-edited porcine embryos. This strategy is predicated on how human cells adapt to a porcine env…
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