Biology of sex differencesAnimalsFemaleMaleParkinson DiseaseSex Characteristics
Sex-dependent immune activation shapes disease progression in a model of Parkinson's disease.
Leah C Beauchamp, Lily A Palumbo, Toby B Lanser, Mariam Baig, Laura M Cox
Published: 202510.1186/s13293-025-00809-1
Abstract
BACKGROUND: While it is clear that inflammation contributes to Parkinson's disease (PD) and prevalence is higher in males, sex remains an underexplored determinant of immune responses in PD. METHODS: Using the 3KL transgenic mouse model, which expres…
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