Stem cell research & therapyAnimalsRabbitsDinoprostoneHumansMesenchymal Stem Cells
MSC administration resolves experimental acute gout increasing specialized pro-resolving mediators synthesis through a super-induction of prostaglandin E2.
Ismael Bermejo-Álvarez, Cristina Vázquez, Alberto Irigaray-Moreno, Ignacio Quevedo-Romero, Aránzazu Mediero, Gabriel Herrero-Beaumont, Raquel Largo
Published: 202510.1186/s13287-025-04877-3
Abstract
BACKGROUND: The resolution of inflammation is an active process triggered in the acute phase of inflammation and mainly directed by specialized pro-resolving mediators (SPMs). Modulating the inflammatory response in favor of resolution is a therapeut…
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