Genome medicine
Genetic liability to psoriasis predicts severe disease outcomes.
Jake R Saklatvala, Samuel Lessard, Maris Teder-Laving, Laurent F Thomas, Ravi Ramessur, Jonas Zierer, Bjørn Olav Åsvold, Anne Barton, David Baudry, John Bowes, Ben Brumpton, Sandro Bruno, Vinod Chandran, Clément Chatelain, Emanuele de Rinaldis
Published: 202510.1186/s13073-025-01561-2
Abstract
BACKGROUND: Psoriasis is a common inflammatory skin disease with heterogeneous presentation. Up to 30% of individuals have severe disease with a greater surface area of skin involvement, co-morbidity burden and impact on quality of life. Prognostic b…
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