Trials
Treatment of Disturbed Sleep in Progressive Supranuclear Palsy: a randomized, remote, double-blinded, 6-week cross-over design study protocol comparing zolpidem, suvorexant, and placebo.
Esther Li, Felicia Song, Quentin Coppola, Leslie Yack, Michael Le, Samirah Javed, Natalie Pandher, Igor Prufer, Olga Mayzel, Hilary H Heuer, Mary Koestler, Bruce L Miller, Adam L Boxer, Lawren Vandevrede, Lea T Grinberg
Published: 202610.1186/s13063-025-09382-9
Abstract
BACKGROUND: Prior research identified profound sleep disruption in progressive supranuclear palsy (PSP). The hypothalamus and brainstem, areas that help regulate sleep/wake patterns, are among the earliest affected brain regions in PSP disease progre…
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