Trials
No more sleepless nights in perimenopause-an open-label, randomized, parallel-group, active controlled intervention study in perimenopausal women with vasomotor symptoms and insomnia to investigate the efficacy of hormone replacement therapy and cognitive behavioral therapy for the treatment of insomnia: study protocol.
Elena Pavicic, Petra Stute, Franziska Rudzik, Antoine Urech, Serena Lozza-Fiacco
Published: 202510.1186/s13063-025-09366-9
Abstract
OBJECTIVES: Cognitive behavioral therapy for insomnia (CBT-I) will be compared with hormone replacement therapy (HRT) and sleep hygiene (active control treatment). BACKGROUND: The late menopausal transition is a vulnerable hormonal phase for women, w…
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