Breast cancer research : BCR
Estrogen metabolism pathways in pregnancy and subsequent breast cancer risk: a prospective follow-up study.
R Troisi, R T Falk, H M Surcel, S Kauppila, T Mirtti, M Gissler, J Sampson, X Xu, S Fan, G L Gierach
Published: 202610.1186/s13058-025-02204-5
Abstract
BACKGROUND: In the years following pregnancy, breast cancer risk is elevated, particularly for hormone receptor negative (HR-) tumors. Exposure to high maternal circulating estrogens, when the breast is vastly remodeling in structure and morphology,…
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