Exosome-derived Menin from cancer-associated fibroblasts promotes gastric cancer progression by activating the HSPA6/JNK/JunD pathway and inducing EMT.

BACKGROUND: Our previous studies found that Menin was highly expressed in gastric cancer (GC) and could promote GC progression. Tumor microenvironment (TME), including cancer-associated fibroblasts (CAFs) and their exosomes plays pivotal roles in GC.…

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