Cell communication and signaling : CCS
Immune cell-based therapies for solid tumors, current challenges and therapeutic advances.
Shukoofeh Torabi, Elham Yekzaman, Soroush Taherkhani, Negin Talachi, Roya Khoshravesh, Arezoo Khosravi, Mahsa Salehi, Ali Zarrabi, Massoud Vosough
Published: 202510.1186/s12964-025-02632-y
Abstract
Solid tumors remain difficult to treat due to antigen heterogeneity, physical barriers that limit immune-cell trafficking, and a profoundly immunosuppressive tumor microenvironment (TME). Over the past decade, cancer immunotherapy advanced considerab…
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