Cell communication and signaling : CCS
LDOC1 connects histone H2B monoubiquitination to tumor cell plasticity in non-small cell lung cancer.
Hsien-Neng Huang, Pin-Feng Hung, Yi-Ta Tsai, En-Ting Liu, Tai-Lung Cha, Ya-Pin Chen, Wen-Tsan Weng, Chiao-Yin Sun, Wei-Hsuan Yu, Hau-Lun Cheng, Chia-Huei Lee
Published: 202610.1186/s12964-025-02607-z
Abstract
BACKGROUND: Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality, partly because epigenetic dysregulation drives tumor progression and metastasis. We previously showed that leucine zipper downregulated in cancer 1 (L…
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