Journal of nanobiotechnology
Low-dose X-ray-activated radiodynamic therapy via a lutetium-coordinated nanoplatform synergizing PARP inhibition and ferroptosis.
Wanli Song, Chuanyi Zhao, Youqing Mai, Guangrong Zhang, Wenyue Kang, Xuanjun Zheng, Qingpeng Yuan, Zeyang Chen, Chengxun Zhong, Junbao Tang, Duoyi Fu, Tiantian Zhai, Kai Ling, Hongyan Jiang
Published: 202610.1186/s12951-026-04027-8
Abstract
Low-dose X-ray-activated radiodynamic therapy (RDT) is a promising strategy for precision oncology. However, its therapeutic efficacy is limited by tumor radioresistance and insufficient generation of reactive oxygen species (ROS). Here, we describe…
Preview only. Read the full abstract at the source